Fission Yeast Polarization: Modeling Cdc42 Oscillations, Symmetry Breaking, and Zones of Activation and Inhibition

Cells polarize for growth, motion, or mating through regulation of membrane-bound small GTPases between active GTP-bound and inactive GDP-bound forms. Activators (GEFs, GTP exchange factors) and inhibitors (GAPs, GTPase activating proteins) provide positive and negative feedbacks. We show that a rea...

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Detalles Bibliográficos
Autores principales: Khalili, Bita, Lovelace, Hailey D., Rutkowski, David M., Holz, Danielle, Vavylonis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464287/
https://www.ncbi.nlm.nih.gov/pubmed/32722101
http://dx.doi.org/10.3390/cells9081769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464287/
https://www.ncbi.nlm.nih.gov/pubmed/32722101
http://dx.doi.org/10.3390/cells9081769

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