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Fission Yeast Polarization: Modeling Cdc42 Oscillations, Symmetry Breaking, and Zones of Activation and Inhibition
Cells polarize for growth, motion, or mating through regulation of membrane-bound small GTPases between active GTP-bound and inactive GDP-bound forms. Activators (GEFs, GTP exchange factors) and inhibitors (GAPs, GTPase activating proteins) provide positive and negative feedbacks. We show that a rea...
Autores principales: | Khalili, Bita, Lovelace, Hailey D., Rutkowski, David M., Holz, Danielle, Vavylonis, Dimitrios |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464287/ https://www.ncbi.nlm.nih.gov/pubmed/32722101 http://dx.doi.org/10.3390/cells9081769 |
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