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MicroRNA-21-Enriched Exosomes as Epigenetic Regulators in Melanomagenesis and Melanoma Progression: The Impact of Western Lifestyle Factors

DNA mutation-induced activation of RAS-BRAF-MEK-ERK signaling associated with intermittent or chronic ultraviolet (UV) irradiation cannot exclusively explain the excessive increase of malignant melanoma (MM) incidence since the 1950s. Malignant conversion of a melanocyte to an MM cell and metastatic...

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Detalles Bibliográficos
Autores principales: Melnik, Bodo C., John, Swen Malte, Carrera-Bastos, Pedro, Schmitz, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464294/
https://www.ncbi.nlm.nih.gov/pubmed/32751207
http://dx.doi.org/10.3390/cancers12082111