Mitochondrion-Directed Nanoparticles Loaded with a Natural Compound and a microRNA for Promoting Cancer Cell Death via the Modulation of Tumor Metabolism and Mitochondrial Dynamics

Mitochondrial dysfunction may cause cancer and metabolic syndrome. Ellagic acid (abbreviated as E), a phytochemical, possesses anticancer activity. MicroRNA 125 (miR-125) may regulate metabolism. However, E has low aqueous solubility, and miR-125 is unstable in a biological fluid. Hence, this study...

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Detalles Bibliográficos
Autores principales: Lo, Yu-Li, Wang, Chen-Shen, Chen, Yen-Chun, Wang, Tse-Yuan, Chang, Yih-Hsin, Chen, Chun-Jung, Yang, Ching-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464316/
https://www.ncbi.nlm.nih.gov/pubmed/32796618
http://dx.doi.org/10.3390/pharmaceutics12080756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464316/
https://www.ncbi.nlm.nih.gov/pubmed/32796618
http://dx.doi.org/10.3390/pharmaceutics12080756

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