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The Temperature-Dependent Effectiveness of Platinum-Based Drugs Mitomycin-C and 5-FU during Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer Cell Lines

Cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is a treatment with curative intent for peritoneal metastasis of colorectal cancer (CRC). Currently, there is no standardized HIPEC protocol: choice of drug, perfusate temperature, and duration of treatment var...

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Detalles Bibliográficos
Autores principales: Helderman, Roxan F.C.P.A., Löke, Daan R., Verhoeff, Jan, Rodermond, Hans M., van Bochove, Gregor G.W., Boon, Menno, van Kesteren, Sanne, Garcia Vallejo, Juan J., Kok, H. Petra, Tanis, Pieter J., Franken, Nicolaas A.P., Crezee, Johannes, Oei, Arlene L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464333/
https://www.ncbi.nlm.nih.gov/pubmed/32722384
http://dx.doi.org/10.3390/cells9081775