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Biopharmaceutical Assessment of Dexamethasone Acetate-Based Hydrogels Combining Hydroxypropyl Cyclodextrins and Polysaccharides for Ocular Delivery

We previously developed two optimized formulations of dexamethasone acetate (DXMa) hydrogels by means of special cubic mixture designs for topical ocular administration. These gels were elaborated with hydroxypropyl-β-CD (HPβCD) and hydroxypropyl-γ-CD (HPγCD) and commercial hydrogels in order to enh...

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Detalles Bibliográficos
Autores principales: Mazet, Roseline, García-Otero, Xurxo, Choisnard, Luc, Wouessidjewe, Denis, Verdoot, Vincent, Bossard, Frédéric, Díaz-Tomé, Victoria, Blanc-Marquis, Véronique, Otero-Espinar, Francisco-Javier, Fernandez-Ferreiro, Anxo, Gèze, Annabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464375/
https://www.ncbi.nlm.nih.gov/pubmed/32751583
http://dx.doi.org/10.3390/pharmaceutics12080717