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Aberrant BUB1 Overexpression Promotes Mitotic Segregation Errors and Chromosomal Instability in Multiple Myeloma

Chromosome instability (CIN), the hallmarks of cancer, reflects ongoing chromosomal changes caused by chromosome segregation errors and results in whole chromosomal or segmental aneuploidy. In multiple myeloma (MM), CIN contributes to the acquisition of tumor heterogeneity, and thereby, to disease p...

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Detalles Bibliográficos
Autores principales: Fujibayashi, Yuto, Isa, Reiko, Nishiyama, Daichi, Sakamoto-Inada, Natsumi, Kawasumi, Norichika, Yamaguchi, Junko, Kuwahara-Ota, Saeko, Matsumura-Kimoto, Yayoi, Tsukamoto, Taku, Chinen, Yoshiaki, Shimura, Yuji, Kobayashi, Tsutomu, Horiike, Shigeo, Taniwaki, Masafumi, Handa, Hiroshi, Kuroda, Junya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464435/
https://www.ncbi.nlm.nih.gov/pubmed/32781708
http://dx.doi.org/10.3390/cancers12082206