Mechanisms of T-Cell Exhaustion in Pancreatic Cancer

T-cell exhaustion is a phenomenon that represents the dysfunctional state of T cells in chronic infections and cancer and is closely associated with poor prognosis in many cancers. The endogenous T-cell immunity and genetically edited cell therapies (CAR-T) failed to prevent tumor immune evasion. Th...

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Detalles Bibliográficos
Autores principales: Saka, Didem, Gökalp, Muazzez, Piyade, Betül, Cevik, Nedim Can, Arik Sever, Elif, Unutmaz, Derya, Ceyhan, Güralp O., Demir, Ihsan Ekin, Asimgil, Hande
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464444/
https://www.ncbi.nlm.nih.gov/pubmed/32823814
http://dx.doi.org/10.3390/cancers12082274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464444/
https://www.ncbi.nlm.nih.gov/pubmed/32823814
http://dx.doi.org/10.3390/cancers12082274

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