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Cisplatin Decreases ENaC Activity Contributing to Renal Salt Wasting Syndrome

Cisplatin (CDDP) is an important anticancer drug. A common side effect of CDDP is renal salt and water-wasting syndrome (RSWS). The origin of RSWS is obscure. Emerging evidence, though, suggests that broad inhibition of sodium transport proteins by CDDP may result in decreases in tubular reabsorptio...

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Detalles Bibliográficos
Autores principales: Soares, Antonio G., Mironova, Elena, Archer, Crystal R., Contreras, Jorge, Stockand, James D., Abd El-Aziz, Tarek Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464492/
https://www.ncbi.nlm.nih.gov/pubmed/32752278
http://dx.doi.org/10.3390/cancers12082140