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Comparison of Structure and Local Dynamics of Two Peptide Dendrimers with the Same Backbone but with Different Side Groups in Their Spacers

In this paper, we perform computer simulation of two lysine-based dendrimers with Lys-2Lys and Lys-2Gly repeating units. These dendrimers were recently studied experimentally by NMR (Sci. Reports, 2018, 8, 8916) and tested as carriers for gene delivery (Bioorg. Chem., 2020, 95, 103504). Simulation w...

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Detalles Bibliográficos
Autores principales: Mikhtaniuk, Sofia E., Bezrodnyi, Valeriy V., Shavykin, Oleg V., Neelov, Igor M., Sheveleva, Nadezhda N., Penkova, Anastasia V., Markelov, Denis A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464546/
https://www.ncbi.nlm.nih.gov/pubmed/32722466
http://dx.doi.org/10.3390/polym12081657