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Distinct conformational states of SARS-CoV-2 spike protein

Intervention strategies are urgently needed to control the SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) pandemic. The trimeric viral spike (S) protein catalyzes fusion between viral and target cell membranes to initiate infection. Here we report two cryo-EM structures, derived from a...

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Detalles Bibliográficos
Autores principales: Cai, Yongfei, Zhang, Jun, Xiao, Tianshu, Peng, Hanqin, Sterling, Sarah M., Walsh, Richard M., Rawson, Shaun, Rits-Volloch, Sophia, Chen, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464562/
https://www.ncbi.nlm.nih.gov/pubmed/32694201
http://dx.doi.org/10.1126/science.abd4251