A Global Gene Body Methylation Measure Correlates Independently with Overall Survival in Solid Cancer Types

Epigenetics, CpG methylation of CpG islands (CGI) and gene bodies (GBs), plays an important role in gene regulation and cancer biology, the former established as a transcription regulator. Genome wide CpG methylation, summarized over GBs and CGIs, was analyzed for impact on overall survival (OS) in...

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Detalles Bibliográficos
Autores principales: Pils, Dietmar, Steindl, Elisabeth, Bachmayr-Heyda, Anna, Dekan, Sabine, Aust, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464642/
https://www.ncbi.nlm.nih.gov/pubmed/32806596
http://dx.doi.org/10.3390/cancers12082257

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464642/
https://www.ncbi.nlm.nih.gov/pubmed/32806596
http://dx.doi.org/10.3390/cancers12082257

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