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Impact of Short-Term Hypoxia on Sirtuins as Regulatory Elements in HUVECs
Background: Sirtuins (SIRT) are NAD(+)-dependent deacetylases that are involved in stress response, antioxidative defense, and longevity via posttranslational modifications. SIRT1 directly activates nitric oxide synthase (NOS). Aging is associated with a reduced sirtuin function and reduction of the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464651/ https://www.ncbi.nlm.nih.gov/pubmed/32796661 http://dx.doi.org/10.3390/jcm9082604 |