S-Adenosylmethionine Treatment of Colorectal Cancer Cell Lines Alters DNA Methylation, DNA Repair and Tumor Progression-Related Gene Expression

Global DNA hypomethylation is a characteristic feature of colorectal carcinoma (CRC). The tumor inhibitory effect of S-adenosylmethionine (SAM) methyl donor has been described in certain cancers including CRC. However, the molecular impact of SAM treatment on CRC cell lines with distinct genetic fea...

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Detalles Bibliográficos
Autores principales: Zsigrai, Sára, Kalmár, Alexandra, Nagy, Zsófia B., Barták, Barbara K., Valcz, Gábor, Szigeti, Krisztina A., Galamb, Orsolya, Dankó, Titanilla, Sebestyén, Anna, Barna, Gábor, Szabó, Vanessza, Pipek, Orsolya, Medgyes-Horváth, Anna, Csabai, István, Tulassay, Zsolt, Igaz, Péter, Takács, István, Molnár, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464653/
https://www.ncbi.nlm.nih.gov/pubmed/32784836
http://dx.doi.org/10.3390/cells9081864

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464653/
https://www.ncbi.nlm.nih.gov/pubmed/32784836
http://dx.doi.org/10.3390/cells9081864

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