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In Vivo Assembly of a Dictyostelium Lamin Mutant Induced by Light, Mechanical Stress, and pH

We expressed Dictyostelium lamin (NE81) lacking both a functional nuclear localization signal and a CAAX-box for C-terminal lipid modification. This lamin mutant assembled into supramolecular, three-dimensional clusters in the cytosol that disassembled at the onset of mitosis and re-assembled in lat...

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Detalles Bibliográficos
Autores principales: Grafe, Marianne, Hofmann, Phillip, Batsios, Petros, Meyer, Irene, Gräf, Ralph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464662/
https://www.ncbi.nlm.nih.gov/pubmed/32759812
http://dx.doi.org/10.3390/cells9081834