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Identification and Pharmaceutical Characterization of a New Itraconazole Terephthalic Acid Cocrystal

The crystallization of poorly soluble drug molecules with an excipient into new solid phases called cocrystals has gained a considerable popularity in the pharmaceutical field. In this work, the cocrystal approach was explored for a very poorly water soluble antifungal active, itraconazole (ITR), wh...

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Detalles Bibliográficos
Autores principales: Machado Cruz, Ricardo, Boleslavská, Tereza, Beránek, Josef, Tieger, Eszter, Twamley, Brendan, Santos-Martinez, Maria Jose, Dammer, Ondřej, Tajber, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464664/
https://www.ncbi.nlm.nih.gov/pubmed/32781726
http://dx.doi.org/10.3390/pharmaceutics12080741