Deletion of the Histone Deacetylase HdaA in Endophytic Fungus Penicillium chrysogenum Fes1701 Induces the Complex Response of Multiple Bioactive Secondary Metabolite Production and Relevant Gene Cluster Expression

Epigenetic regulation plays a critical role in controlling fungal secondary metabolism. Here, we report the pleiotropic effects of the epigenetic regulator HdaA (histone deacetylase) on secondary metabolite production and the associated biosynthetic gene clusters (BGCs) expression in the plant endop...

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Detalles Bibliográficos
Autores principales: Ding, Zhuang, Zhou, Haibo, Wang, Xiao, Huang, Huiming, Wang, Haotian, Zhang, Ruiyan, Wang, Zhengping, Han, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464707/
https://www.ncbi.nlm.nih.gov/pubmed/32796640
http://dx.doi.org/10.3390/molecules25163657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464707/
https://www.ncbi.nlm.nih.gov/pubmed/32796640
http://dx.doi.org/10.3390/molecules25163657

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