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ROS Dependent Wnt/β-Catenin Pathway and Its Regulation on Defined Micro-Pillars—A Combined In Vitro and In Silico Study

The physico-chemical surface design of implants influences the surrounding cells. Osteoblasts on sharp-edged micro-topographies revealed an impaired cell phenotype, function and Ca(2+) mobilization. The influence of edges and ridges on the Wnt/β-catenin pathway in combination with the cells’ stress...

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Detalles Bibliográficos
Autores principales: Staehlke, Susanne, Haack, Fiete, Waldner, Anna-Christin, Koczan, Dirk, Moerke, Caroline, Mueller, Petra, Uhrmacher, Adelinde M., Nebe, J. Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464713/
https://www.ncbi.nlm.nih.gov/pubmed/32726949
http://dx.doi.org/10.3390/cells9081784