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ROS Dependent Wnt/β-Catenin Pathway and Its Regulation on Defined Micro-Pillars—A Combined In Vitro and In Silico Study
The physico-chemical surface design of implants influences the surrounding cells. Osteoblasts on sharp-edged micro-topographies revealed an impaired cell phenotype, function and Ca(2+) mobilization. The influence of edges and ridges on the Wnt/β-catenin pathway in combination with the cells’ stress...
Autores principales: | Staehlke, Susanne, Haack, Fiete, Waldner, Anna-Christin, Koczan, Dirk, Moerke, Caroline, Mueller, Petra, Uhrmacher, Adelinde M., Nebe, J. Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464713/ https://www.ncbi.nlm.nih.gov/pubmed/32726949 http://dx.doi.org/10.3390/cells9081784 |
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