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Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy

Antimicrobial peptides (AMPs) are a class of molecules that play an essential role in innate immune regulation. The Brevinin-1 family are AMPs that show strong pharmacological and antimicrobial potential. A novel peptide, B1A, was designed based on the primary structure of brevinin-1PLb and brevinin...

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Detalles Bibliográficos
Autores principales: He, Haoyang, Chen, Yuqing, Ye, Zhuming, Chen, Xiaoling, Ma, Chengbang, Zhou, Mei, Xi, Xinping, Burrows, James F., Chen, Tianbao, Wang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464788/
https://www.ncbi.nlm.nih.gov/pubmed/32781587
http://dx.doi.org/10.3390/biology9080209