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Modification and Targeted Design of N-Terminal Truncates Derived from Brevinin with Improved Therapeutic Efficacy
Antimicrobial peptides (AMPs) are a class of molecules that play an essential role in innate immune regulation. The Brevinin-1 family are AMPs that show strong pharmacological and antimicrobial potential. A novel peptide, B1A, was designed based on the primary structure of brevinin-1PLb and brevinin...
Autores principales: | He, Haoyang, Chen, Yuqing, Ye, Zhuming, Chen, Xiaoling, Ma, Chengbang, Zhou, Mei, Xi, Xinping, Burrows, James F., Chen, Tianbao, Wang, Lei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464788/ https://www.ncbi.nlm.nih.gov/pubmed/32781587 http://dx.doi.org/10.3390/biology9080209 |
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