Uptake Study in Lysosome-Enriched Fraction: Critical Involvement of Lysosomal Trapping in Quinacrine Uptake but Not Fluorescence-Labeled Verapamil Transport at Blood-Retinal Barrier

Lysosomal trapping at the blood–retinal barrier (BRB) was investigated through quinacrine and fluorescence-labeled verapamil (EFV) uptake. Quinacrine uptake by conditionally immortalized rat retinal capillary endothelial (TR-iBRB2) cells suggested saturable and non-saturable transport processes in t...

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Detalles Bibliográficos
Autores principales: Kubo, Yoshiyuki, Yamada, Miki, Konakawa, Saki, Akanuma, Shin-ichi, Hosoya, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464812/
https://www.ncbi.nlm.nih.gov/pubmed/32784408
http://dx.doi.org/10.3390/pharmaceutics12080747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464812/
https://www.ncbi.nlm.nih.gov/pubmed/32784408
http://dx.doi.org/10.3390/pharmaceutics12080747

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