The HECT E3 Ligase E6AP/UBE3A as a Therapeutic Target in Cancer and Neurological Disorders

The HECT (Homologous to the E6-AP Carboxyl Terminus)-family protein E6AP (E6-associated protein), encoded by the UBE3A gene, is a multifaceted ubiquitin ligase that controls diverse signaling pathways involved in cancer and neurological disorders. The oncogenic role of E6AP in papillomavirus-induced...

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Detalles Bibliográficos
Autores principales: Owais, Asia, Mishra, Rama K., Kiyokawa, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464832/
https://www.ncbi.nlm.nih.gov/pubmed/32751183
http://dx.doi.org/10.3390/cancers12082108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464832/
https://www.ncbi.nlm.nih.gov/pubmed/32751183
http://dx.doi.org/10.3390/cancers12082108

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