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The Function of BARD1 in Centrosome Regulation in Cooperation with BRCA1/OLA1/RACK1

Breast cancer gene 1 (BRCA1)-associated RING domain protein 1 (BARD1) forms a heterodimer with BRCA1, a tumor suppressor associated with hereditary breast and ovarian cancer. BRCA1/BARD1 functions in multiple cellular processes including DNA repair and centrosome regulation. Centrosomes are the majo...

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Detalles Bibliográficos
Autores principales: Otsuka, Kei, Yoshino, Yuki, Qi, Huicheng, Chiba, Natsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464954/
https://www.ncbi.nlm.nih.gov/pubmed/32722046
http://dx.doi.org/10.3390/genes11080842