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Carcinoma-Associated Mesenchymal Stem Cells Promote Chemoresistance in Ovarian Cancer Stem Cells via PDGF Signaling

Within the ovarian cancer tumor microenvironment, cancer stem-like cells (CSC) interact with carcinoma associated mesenchymal stem/stromal cells (CA-MSC) through multiple secreted cytokines and growth factors. These paracrine interactions have been revealed to cause enrichment of CSC and their chemo...

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Detalles Bibliográficos
Autores principales: Raghavan, Shreya, Snyder, Catherine S., Wang, Anni, McLean, Karen, Zamarin, Dmitriy, Buckanovich, Ronald J., Mehta, Geeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464970/
https://www.ncbi.nlm.nih.gov/pubmed/32726910
http://dx.doi.org/10.3390/cancers12082063