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Carcinoma-Associated Mesenchymal Stem Cells Promote Chemoresistance in Ovarian Cancer Stem Cells via PDGF Signaling
Within the ovarian cancer tumor microenvironment, cancer stem-like cells (CSC) interact with carcinoma associated mesenchymal stem/stromal cells (CA-MSC) through multiple secreted cytokines and growth factors. These paracrine interactions have been revealed to cause enrichment of CSC and their chemo...
Autores principales: | Raghavan, Shreya, Snyder, Catherine S., Wang, Anni, McLean, Karen, Zamarin, Dmitriy, Buckanovich, Ronald J., Mehta, Geeta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7464970/ https://www.ncbi.nlm.nih.gov/pubmed/32726910 http://dx.doi.org/10.3390/cancers12082063 |
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