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Synthesis and Initial Evaluation of a Novel Fluorophore for Selective FMDV 3C Protease Detection

The development and evaluation of a Boc-AL(Boc)Q(Trt)-AMC fluorophore to detect 3C Protease, produced by Foot and Mouth Disease Virus (FMDV) is reported, with a view to a potential use as a rapid screen for FMDV infected livestock The peptide-linked conjugate fluorophore is evaluated in vitro for se...

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Detalles Bibliográficos
Autores principales: Malik, Samerah, Sinclair, Alex, Ryan, Ali, Le Gresley, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465021/
https://www.ncbi.nlm.nih.gov/pubmed/32784761
http://dx.doi.org/10.3390/molecules25163599