Comprehensive Genomic Analysis Reveals the Prognostic Role of LRRK2 Copy-Number Variations in Human Malignancies

Genetic alterations of leucine-rich repeat kinase 2 (LRRK2), one of the most important contributors to familial Parkinson’s disease (PD), have been hypothesized to play a role in cancer development due to demographical and preclinical data. Here, we sought to define the prevalence and prognostic sig...

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Detalles Bibliográficos
Autores principales: Lopez, Gianluca, Lazzeri, Giulia, Rappa, Alessandra, Isimbaldi, Giuseppe, Cribiù, Fulvia Milena, Guerini-Rocco, Elena, Ferrero, Stefano, Vaira, Valentina, Di Fonzo, Alessio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465025/
https://www.ncbi.nlm.nih.gov/pubmed/32722212
http://dx.doi.org/10.3390/genes11080846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465025/
https://www.ncbi.nlm.nih.gov/pubmed/32722212
http://dx.doi.org/10.3390/genes11080846

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