Human FBXL8 Is a Novel E3 Ligase Which Promotes BRCA Metastasis by Stimulating Pro-Tumorigenic Cytokines and Inhibiting Tumor Suppressors

The initiation and progression of breast cancer (BRCA) is associated with inflammation and immune-overactivation, which is critically modulated by the E3 ubiquitin ligase. However, the underlying mechanisms and key factors involved in BRCA formation and disease advancement remains under-explored. By...

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Detalles Bibliográficos
Autores principales: Chang, Shu-Chun, Hsu, Wayne, Su, Emily Chia-Yu, Hung, Chin-Sheng, Ding, Jeak Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465060/
https://www.ncbi.nlm.nih.gov/pubmed/32784654
http://dx.doi.org/10.3390/cancers12082210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465060/
https://www.ncbi.nlm.nih.gov/pubmed/32784654
http://dx.doi.org/10.3390/cancers12082210

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