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Endogenous Carbon Monoxide Signaling Modulates Mitochondrial Function and Intracellular Glucose Utilization: Impact of the Heme Oxygenase Substrate Hemin

Stress-inducible heme oxygenase-1 (HO-1) catalyzes the oxidative cleavage of heme yielding biliverdin, ferrous iron, and carbon monoxide (CO). Heme oxygenase activity has been attributed to antioxidant defense via the redox cycling system of biliverdin and bilirubin. There is increasing evidence tha...

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Detalles Bibliográficos
Autores principales: Stucki, David, Steinhausen, Julia, Westhoff, Philipp, Krahl, Heide, Brilhaus, Dominik, Massenberg, Annika, Weber, Andreas P. M., Reichert, Andreas S., Brenneisen, Peter, Stahl, Wilhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465082/
https://www.ncbi.nlm.nih.gov/pubmed/32717801
http://dx.doi.org/10.3390/antiox9080652