Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy

Some colorectal cancer patients harboring FGFR (fibroblast growth factor receptor) genetic alterations, such as copy number gain, mutation, and/or mRNA overexpression, were selected for enrollment in several recent clinical trials of FGFR inhibitor, because these genetic alterations were preclinical...

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Detalles Bibliográficos
Autores principales: Yamamoto, Takehito, Miyoshi, Hiroyuki, Kakizaki, Fumihiko, Maekawa, Hisatsugu, Yamaura, Tadayoshi, Morimoto, Tomonori, Katayama, Toshiro, Kawada, Kenji, Sakai, Yoshiharu, Taketo, M. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465102/
https://www.ncbi.nlm.nih.gov/pubmed/32708005
http://dx.doi.org/10.3390/cancers12082010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465102/
https://www.ncbi.nlm.nih.gov/pubmed/32708005
http://dx.doi.org/10.3390/cancers12082010

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