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A Cell-Based Reporter Assay for Screening Inhibitors of MERS Coronavirus RNA-Dependent RNA Polymerase Activity

Severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), and coronavirus disease 2019 (COVID-19) are emerging zoonotic diseases caused by coronavirus (CoV) infections. The viral RNA-dependent RNA polymerase (RdRp) has been suggested as a valuable target for antiviral therap...

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Detalles Bibliográficos
Autores principales: Min, Jung Sun, Kim, Geon-Woo, Kwon, Sunoh, Jin, Young-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465106/
https://www.ncbi.nlm.nih.gov/pubmed/32727069
http://dx.doi.org/10.3390/jcm9082399