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A Linear Regression and Deep Learning Approach for Detecting Reliable Genetic Alterations in Cancer Using DNA Methylation and Gene Expression Data

DNA methylation change has been useful for cancer biomarker discovery, classification, and potential treatment development. So far, existing methods use either differentially methylated CpG sites or combined CpG sites, namely differentially methylated regions, that can be mapped to genes. However, s...

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Detalles Bibliográficos
Autores principales: Mallik, Saurav, Seth, Soumita, Bhadra, Tapas, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465138/
https://www.ncbi.nlm.nih.gov/pubmed/32806782
http://dx.doi.org/10.3390/genes11080931