Development of [(18)F]ICMT-11 for Imaging Caspase-3/7 Activity during Therapy-Induced Apoptosis

Insufficient apoptosis is a recognised hallmark of cancer. A strategy to quantitatively measure apoptosis in vivo would be of immense value in both drug discovery and routine patient management. The first irreversible step in the apoptosis cascade is activation of the “executioner” caspase-3 enzyme...

Descripción completa

Detalles Bibliográficos
Autores principales: García-Argüello, Segundo Francisco, Lopez-Lorenzo, Beatriz, Cornelissen, Bart, Smith, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465189/
https://www.ncbi.nlm.nih.gov/pubmed/32781531
http://dx.doi.org/10.3390/cancers12082191

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465189/
https://www.ncbi.nlm.nih.gov/pubmed/32781531
http://dx.doi.org/10.3390/cancers12082191

Ejemplares similares