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A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies

The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in different components, Peceol, Kolliphor EL, and Transcutol were selected as excipients. Pseudo-ternary phase diagrams were constr...

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Detalles Bibliográficos
Autores principales: Alghananim, Alaa, Özalp, Yıldız, Mesut, Burcu, Serakinci, Nedime, Özsoy, Yıldız, Güngör, Sevgi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465256/
https://www.ncbi.nlm.nih.gov/pubmed/32722238
http://dx.doi.org/10.3390/ph13080162