Cargando…

A Solid Ultra Fine Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) of Deferasirox for Improved Solubility: Optimization, Characterization, and In Vitro Cytotoxicity Studies

The research work was designed to develop a solid self-nanoemulsifying drug delivery system (S-SNEDDS) of deferasirox (DFX). According to the solubility studies of DFX in different components, Peceol, Kolliphor EL, and Transcutol were selected as excipients. Pseudo-ternary phase diagrams were constr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alghananim, Alaa, Özalp, Yıldız, Mesut, Burcu, Serakinci, Nedime, Özsoy, Yıldız, Güngör, Sevgi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465256/ https://www.ncbi.nlm.nih.gov/pubmed/32722238 http://dx.doi.org/10.3390/ph13080162

Ejemplares similares

In Vitro Evaluation of a Solid Supersaturated Self Nanoemulsifying Drug Delivery System (Super-SNEDDS) of Aprepitant for Enhanced Solubility
por: Nazlı, Hakan, et al.
Publicado: (2021)

Enhancement of the Solubility and Bioavailability of Pitavastatin through a Self-Nanoemulsifying Drug Delivery System (SNEDDS)
por: Ashfaq, Mehran, et al.
Publicado: (2022)

Preparation of Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDS) by Co-Extrusion of Liquid SNEDDS and Polymeric Carriers—A New and Promising Formulation Approach to Improve the Solubility of Poorly Water-Soluble Drugs
por: Schmied, Fabian-Pascal, et al.
Publicado: (2022)

Optimization of the Micellar-Based In Situ Gelling Systems Posaconazole with Quality by Design (QbD) Approach and Characterization by In Vitro Studies
por: Durgun, Meltem Ezgi, et al.
Publicado: (2022)

Evaluation of Self-Nanoemulsifying Drug Delivery Systems (SNEDDS) for Poorly Water-Soluble Talinolol: Preparation, in vitro and in vivo Assessment
por: Kazi, Mohsin, et al.
Publicado: (2019)

A comprehensive study of the basic formulation of supersaturated self-nanoemulsifying drug delivery systems (SNEDDS) of albendazolum
por: Alothaid, Hani, et al.
Publicado: (2021)

Self-Nanoemulsifying Drug Delivery System (SNEDDS) of Apremilast: In Vitro Evaluation and Pharmacokinetics Studies
por: Abushal, Ahad S., et al.
Publicado: (2022)

Biopolymer-Based Nanogel Approach in Drug Delivery: Basic Concept and Current Developments
por: Altuntaş, Ebru, et al.
Publicado: (2023)

Acute Oral Toxicity Evaluation of Andrographolide Self-Nanoemulsifying Drug Delivery System (SNEDDS) Formulation
por: Ramadani, Arba Pramundita, et al.
Publicado: (2021)

Self-Nanoemulsifying Drug Delivery System (SNEDDS) for Improved Oral Bioavailability of Chlorpromazine: In Vitro and In Vivo Evaluation
por: Baloch, Jeand, et al.
Publicado: (2019)

Bioactive Self-Nanoemulsifying Drug Delivery Systems (Bio-SNEDDS) for Combined Oral Delivery of Curcumin and Piperine
por: Kazi, Mohsin, et al.
Publicado: (2020)

A Customized Screening Tool Approach for the Development of a Self-Nanoemulsifying Drug Delivery System (SNEDDS)
por: Schmied, Fabian-Pascal, et al.
Publicado: (2021)

Self-nanoemulsifying drug delivery system (SNEDDS) mediated improved oral bioavailability of thymoquinone: optimization, characterization, pharmacokinetic, and hepatotoxicity studies
por: Rathore, Charul, et al.
Publicado: (2022)

Design and Optimization of Pioglitazone Hydrochloride Self-Nanoemulsifying Drug Delivery System (SNEDDS) Incorporated into an Orally Disintegrating Tablet
por: Teaima, Mahmoud, et al.
Publicado: (2022)

Systematic Screening Study for the Selection of Proper Stabilizers to Produce Physically Stable Canagliflozin Nanosuspension by Wet Milling Method
por: Pirincci Tok, Yagmur, et al.
Publicado: (2023)

Preparation, characterization, and in vivo evaluation of a self-nanoemulsifying drug delivery system (SNEDDS) loaded with morin-phospholipid complex
por: Zhang, Jinjie, et al.
Publicado: (2011)

Preparation, characterization, and evaluation of antioxidant activity and bioavailability of a self-nanoemulsifying drug delivery system (SNEDDS) for buckwheat flavonoids
por: Zhao, Zhijuan, et al.
Publicado: (2020)

Nasal Delivery of High Molecular Weight Drugs
por: Ozsoy, Yıldız, et al.
Publicado: (2009)

Development of Alectinib-Suspended SNEDDS for Enhanced Solubility and Dissolution
por: Park, Eun Ji, et al.
Publicado: (2022)

Erratum to: Preparation, characterization, and evaluation of antioxidant activity and bioavailability of a self-nanoemulsifying drug delivery system (SNEDDS) for buckwheat flavonoids
por: Zhao, Zhijuan, et al.
Publicado: (2021)

Novel Solid Self-Nanoemulsifying Drug Delivery System (S-SNEDDS) for Oral Delivery of Olmesartan Medoxomil: Design, Formulation, Pharmacokinetic and Bioavailability Evaluation
por: Nasr, Ali, et al.
Publicado: (2016)

Tissue-Specific Ultra-Short Telomeres in Chronic Obstructive Pulmonary Disease
por: Cagsin, Huseyin, et al.
Publicado: (2020)

Enhancing Oral Bioavailability of Apigenin Using a Bioactive Self-Nanoemulsifying Drug Delivery System (Bio-SNEDDS): In Vitro, In Vivo and Stability Evaluations
por: Kazi, Mohsin, et al.
Publicado: (2020)

Effects of Pegagan (Centella asiatica L.) Ethanolic Extract SNEDDS (Self-nanoemulsifying Drug Delivery Systems) on the Development of Zebrafish (Danio rerio) Embryos
por: Hayati, Farida, et al.
Publicado: (2020)

Reduced the Food Effect and Enhanced the Oral Bioavailability of Ivacaftor by Self-Nanoemulsifying Drug Delivery System (SNEDDS) Using a New Oil Phase
por: Miao, Yanfei, et al.
Publicado: (2022)

Orlistat-loaded solid SNEDDS for the enhanced solubility, dissolution, and in vivo performance
por: Kim, Dae Hun, et al.
Publicado: (2018)

Adsorbent Precoating by Lyophilization: A Novel Green Solvent Technique to Enhance Cinnarizine Release from Solid Self-Nanoemulsifying Drug Delivery Systems (S-SNEDDS)
por: Tashish, Ahmad Yousef, et al.
Publicado: (2022)

Optimization and Characterization of Chitosan Films for Transdermal Delivery of Ondansetron
por: Can, Aslı Sedef, et al.
Publicado: (2013)

A Novel Semi-Solid Self-Emulsifying Formulation of Aprepitant for Oral Delivery: An In Vitro Evaluation
por: Nazlı, Hakan, et al.
Publicado: (2023)

Flurbiprofen-Loaded Solid SNEDDS Preconcentrate for the Enhanced Solubility, In-Vitro Dissolution and Bioavailability in Rats
por: Kim, Rae Man, et al.
Publicado: (2018)

Colloidal nanocarriers for the enhanced cutaneous delivery of naftifine: characterization studies and in vitro and in vivo evaluations
por: Erdal, M Sedef, et al.
Publicado: (2016)

Nanofibers in Ocular Drug Targeting and Tissue Engineering: Their Importance, Advantages, Advances, and Future Perspectives
por: Uzel, Egemen, et al.
Publicado: (2023)

Estimating the Optimal Dexketoprofen Pharmaceutical Formulation with Machine Learning Methods and Statistical Approaches
por: Başkor, Atakan, et al.
Publicado: (2021)

Telomerase activity in human leukemic cells with or without monosomy 7 or 7q-
por: Serakinci, Nedime, et al.
Publicado: (2002)

Risk Prediction Model Development for Late On-Set Breast Cancer Screening in Low- and Middle-Income Societies: A Model Study for North Cyprus
por: Danladi, Ceasar Dubor, et al.
Publicado: (2020)

SNEDDS Containing Poorly Water Soluble Cinnarizine; Development and in Vitro Characterization of Dispersion, Digestion and Solubilization
por: Larsen, Anne T., et al.
Publicado: (2012)

Expression of TRF2 and its prognostic relevance in advanced stage cervical cancer patients
por: Ozden, Sevgi, et al.
Publicado: (2014)

A Novel TBX19 Gene Mutation in a Case of Congenital Isolated Adrenocorticotropic Hormone Deficiency Presenting with Recurrent Respiratory Tract Infections
por: Akcan, Nese, et al.
Publicado: (2017)

A novel solid self-nanoemulsifying drug delivery system (S-SNEDDS) for improved stability and oral bioavailability of an oily drug, 1-palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol
por: Kim, Kyeong Soo, et al.
Publicado: (2017)

Updated North Cyprus response status for COVID-19 in comparison with similar country sizes. Highlights on the importance of population per square meter
por: Serakinci, Nedime, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gj6jea05nhupc7ceh67lumdmag