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Prediction of Drug-Induced Hyperbilirubinemia by In Vitro Testing
Bilirubin, the end product of heme catabolism, is produced continuously in the body and may reach toxic levels if accumulates in the serum and tissues; therefore, a highly efficient mechanism evolved for its disposition. Normally, unconjugated bilirubin enters hepatocytes through the uptake transpor...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465333/ https://www.ncbi.nlm.nih.gov/pubmed/32796590 http://dx.doi.org/10.3390/pharmaceutics12080755 |