Piperazine- and Piperidine-Containing Thiazolo[5,4-d]pyrimidine Derivatives as New Potent and Selective Adenosine A(2A) Receptor Inverse Agonists

The therapeutic use of A(2A) adenosine receptor (AR) antagonists for the treatment of neurodegenerative disorders, such as Parkinson and Alzheimer diseases, is a very promising approach. Moreover, the potential therapeutic role of A(2A) AR antagonists to avoid both immunoescaping of tumor cells and...

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Detalles Bibliográficos
Autores principales: Varano, Flavia, Catarzi, Daniela, Vigiani, Erica, Vincenzi, Fabrizio, Pasquini, Silvia, Varani, Katia, Colotta, Vittoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465344/
https://www.ncbi.nlm.nih.gov/pubmed/32722122
http://dx.doi.org/10.3390/ph13080161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465344/
https://www.ncbi.nlm.nih.gov/pubmed/32722122
http://dx.doi.org/10.3390/ph13080161

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