Exosomal miR-223 derived from natural killer cells inhibits hepatic stellate cell activation by suppressing autophagy

BACKGROUND: Activation of hepatic stellate cells (HSCs) is a prominent driver of liver fibrosis. We previously demonstrated that exosomes derived from natural killer (NK) cells (NK-Exo) attenuated TGF-β1-induced HSC activation. Herein, this study was designed to investigate the mechanism underlying...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Wang, Yinghao, Quan, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465359/
https://www.ncbi.nlm.nih.gov/pubmed/32873229
http://dx.doi.org/10.1186/s10020-020-00207-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465359/
https://www.ncbi.nlm.nih.gov/pubmed/32873229
http://dx.doi.org/10.1186/s10020-020-00207-w

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