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Exosomal miR-223 derived from natural killer cells inhibits hepatic stellate cell activation by suppressing autophagy
BACKGROUND: Activation of hepatic stellate cells (HSCs) is a prominent driver of liver fibrosis. We previously demonstrated that exosomes derived from natural killer (NK) cells (NK-Exo) attenuated TGF-β1-induced HSC activation. Herein, this study was designed to investigate the mechanism underlying...
Autores principales: | Wang, Ling, Wang, Yinghao, Quan, Jun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465359/ https://www.ncbi.nlm.nih.gov/pubmed/32873229 http://dx.doi.org/10.1186/s10020-020-00207-w |
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