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Displacement of Slow-Turnover DNA Glycosylases by Molecular Traffic on DNA

In the base excision repair pathway, the initiating enzymes, DNA glycosylases, remove damaged bases and form long-living complexes with the abasic DNA product, but can be displaced by AP endonucleases. However, many nuclear proteins can move along DNA, either actively (such as DNA or RNA polymerases...

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Detalles Bibliográficos
Autores principales: Yudkina, Anna V., Endutkin, Anton V., Diatlova, Eugenia A., Moor, Nina A., Vokhtantsev, Ivan P., Grin, Inga R., Zharkov, Dmitry O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465369/
https://www.ncbi.nlm.nih.gov/pubmed/32751599
http://dx.doi.org/10.3390/genes11080866