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The Intrinsically Disordered W Protein Is Multifunctional during Henipavirus Infection, Disrupting Host Signalling Pathways and Nuclear Import

Nipah and Hendra viruses are highly pathogenic, zoonotic henipaviruses that encode proteins that inhibit the host’s innate immune response. The W protein is one of four products encoded from the P gene and binds a number of host proteins to regulate signalling pathways. The W protein is intrinsicall...

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Detalles Bibliográficos
Autores principales: Tsimbalyuk, Sofiya, Cross, Emily M., Hoad, Mikayla, Donnelly, Camilla M., Roby, Justin A., Forwood, Jade K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465373/
https://www.ncbi.nlm.nih.gov/pubmed/32824665
http://dx.doi.org/10.3390/cells9081913