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Cigarette Smoke Extract Stimulates MMP-2 Production in Nasal Fibroblasts via ROS/PI3K, Akt, and NF-κB Signaling Pathways

Cigarette smoke exposure has been shown to be associated with chronic rhinosinusitis and tissue remodeling. The present study aimed to investigate the effects of cigarette smoke extract (CSE) on matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) production in nasal fibro...

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Detalles Bibliográficos
Autores principales: Park, Joo-Hoo, Shin, Jae-Min, Yang, Hyun-Woo, Kim, Tae Hoon, Lee, Seung Hoon, Lee, Heung-Man, Cho, Jae-Gu, Park, Il-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465436/
https://www.ncbi.nlm.nih.gov/pubmed/32806646
http://dx.doi.org/10.3390/antiox9080739