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Anti-Cancer Immunotherapies Targeting Telomerase

Telomerase is a reverse transcriptase that maintains telomeres length, compensating for the attrition of chromosomal ends that occurs during each replication cycle. Telomerase is expressed in germ cells and stem cells, whereas it is virtually undetectable in adult somatic cells. On the other hand, t...

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Detalles Bibliográficos
Autores principales: Negrini, Simone, De Palma, Raffaele, Filaci, Gilberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465444/
https://www.ncbi.nlm.nih.gov/pubmed/32806719
http://dx.doi.org/10.3390/cancers12082260