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Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy

Expression of ATP-binding cassette (ABC) transporters has long been implicated in cancer chemotherapy resistance. Increased expression of the ABCC subfamily transporters has been reported in prostate cancer, especially in androgen-resistant cases. ABCC transporters are known to efflux drugs but, rec...

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Detalles Bibliográficos
Autores principales: Emmanouilidi, Aikaterini, Casari, Ilaria, Gokcen Akkaya, Begum, Maffucci, Tania, Furic, Luc, Guffanti, Federica, Broggini, Massimo, Chen, Xi, Maxuitenko, Yulia Y., Keeton, Adam B., Piazza, Gary A., Linton, Kenneth J., Falasca, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465469/
https://www.ncbi.nlm.nih.gov/pubmed/32718079
http://dx.doi.org/10.3390/cancers12082022