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MPN: The Molecular Drivers of Disease Initiation, Progression and Transformation and their Effect on Treatment

Myeloproliferative neoplasms (MPNs) constitute a group of disorders identified by an overproduction of cells derived from myeloid lineage. The majority of MPNs have an identifiable driver mutation responsible for cytokine-independent proliferative signalling. The acquisition of coexisting mutations...

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Detalles Bibliográficos
Autores principales: Grabek, Julian, Straube, Jasmin, Bywater, Megan, Lane, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465511/
https://www.ncbi.nlm.nih.gov/pubmed/32823933
http://dx.doi.org/10.3390/cells9081901