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MPN: The Molecular Drivers of Disease Initiation, Progression and Transformation and their Effect on Treatment
Myeloproliferative neoplasms (MPNs) constitute a group of disorders identified by an overproduction of cells derived from myeloid lineage. The majority of MPNs have an identifiable driver mutation responsible for cytokine-independent proliferative signalling. The acquisition of coexisting mutations...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465511/ https://www.ncbi.nlm.nih.gov/pubmed/32823933 http://dx.doi.org/10.3390/cells9081901 |