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Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions

Genetically engineered mouse models (GEMM) are an elegant tool to study liver carcinogenesis in vivo. Newly designed mouse models need detailed (histopathological) phenotyping when described for the first time to avoid misinterpretation and misconclusions. Many chemically induced models for hepatoca...

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Detalles Bibliográficos
Autores principales: Steiger, Katja, Gross, Nina, Widholz, Sebastian A., Rad, Roland, Weichert, Wilko, Mogler, Carolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465606/
https://www.ncbi.nlm.nih.gov/pubmed/32823526
http://dx.doi.org/10.3390/cancers12082265