DNA Methyltransferases in Cancer: Biology, Paradox, Aberrations, and Targeted Therapy

DNA methyltransferases are an essential class of modifiers in epigenetics. In mammals, DNMT1, DNMT3A and DNMT3B participate in DNA methylation to regulate normal biological functions, such as embryo development, cell differentiation and gene transcription. Aberrant functions of DNMTs are frequently...

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Detalles Bibliográficos
Autores principales: Zhang, Jiayu, Yang, Cheng, Wu, Chunfu, Cui, Wei, Wang, Lihui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465608/
https://www.ncbi.nlm.nih.gov/pubmed/32751889
http://dx.doi.org/10.3390/cancers12082123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465608/
https://www.ncbi.nlm.nih.gov/pubmed/32751889
http://dx.doi.org/10.3390/cancers12082123

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