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Plasmodium falciparum Knockout for the GPCR-Like PfSR25 Receptor Displays Greater Susceptibility to 1,2,3-Triazole Compounds That Block Malaria Parasite Development

The search for new compounds with antimalarial activity is urgent, as resistance to ones in the classical drug, has already been described in more than one continent. Compounds derived from 1,2,3-triazoles are effective against parasites and bacteria. Here, we evaluated the potential antimalarial ac...

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Detalles Bibliográficos
Autores principales: dos Santos, Benedito M., Gonzaga, Daniel T. G., da Silva, Fernando C., Ferreira, Vitor F., Garcia, Celia R. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465636/
https://www.ncbi.nlm.nih.gov/pubmed/32824696
http://dx.doi.org/10.3390/biom10081197