Cargando…
Plasmodium falciparum Knockout for the GPCR-Like PfSR25 Receptor Displays Greater Susceptibility to 1,2,3-Triazole Compounds That Block Malaria Parasite Development
The search for new compounds with antimalarial activity is urgent, as resistance to ones in the classical drug, has already been described in more than one continent. Compounds derived from 1,2,3-triazoles are effective against parasites and bacteria. Here, we evaluated the potential antimalarial ac...
Autores principales: | dos Santos, Benedito M., Gonzaga, Daniel T. G., da Silva, Fernando C., Ferreira, Vitor F., Garcia, Celia R. S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465636/ https://www.ncbi.nlm.nih.gov/pubmed/32824696 http://dx.doi.org/10.3390/biom10081197 |
Ejemplares similares
-
The Knockout for G Protein-Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds
por: Santos, Benedito M., et al.
Publicado: (2021) -
PfsR Is a Key Regulator of Iron Homeostasis in Synechocystis PCC 6803
por: Cheng, Dan, et al.
Publicado: (2014) -
Plasmodium falciparum GPCR-like receptor SR25 mediates extracellular K(+) sensing coupled to Ca(2+) signaling and stress survival
por: Moraes, Miriam S., et al.
Publicado: (2017) -
1,2,3-Triazoles
por: Rachwal, S., et al.
Publicado: (2008) -
Monitoring PfMDR1 transport in Plasmodium falciparum
por: Reiling, Sarah J, et al.
Publicado: (2015)